One of the deaths involved a New York adult with several underlying health conditions, said Lola Scott Russell, a spokeswoman for the Centers for Disease Control and Prevention. The other is a death previously reported by New Hampshire, where state health officials said a patient died due to complications.

Russell said all but three of the suspected infections are in the northeastern U.S. and 18 are in New England.

Ashville, New York-based Fairbank Farms recalled almost 546,000 pounds (247,664 kilograms) of fresh ground beef that had been distributed in September to stores from North Carolina to Maine. The U.S. Department of Agriculture's recall notice, dated Saturday, said that the possibly tainted meat had been sold in numerous ways, from meatloaf and meatball mix to hamburger patties.

Located in the southwestern corner of New York a few miles (kilometers) from the Pennsylvania line, Fairbank Farms has had two other voluntary recalls over the last two years, according to the USDA's Food Safety and Inspection Service.

In September 2007, the company recalled 884 pounds (401 kilograms) of ground beef products because they may have been contaminated with E. coli, the agency said. And in May 2008, it recalled 22,481 pounds (10,197 kilograms) of ground beef products that may have contained pieces of plastic.

Symptoms of E. coli infections include stomach cramps that may be severe and diarrhea that may turn bloody within one to three days. E. coli infections can sometimes lead to complications including kidney failure.

Symptoms usually show up three to four days after a person eats contaminated food, although in some cases it can be as long as eight days. Officials said anyone having symptoms should immediately contact a doctor.

Russell, the CDC spokeswoman, said the E. coli strain involved in the recall, 0157:H7, infects about 70,000 Americans a year and kills 52.

After dropping for a few years, annual recalls of ground beef and other beef products contaminated with E. coli have rebounded, with at least a dozen recalls through October 2009, according to USDA data.

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On the Net:

http://www.fairbankfarms.com/